12 EuReCa PhD Program International Positions in France

Eligibility Criteria

• Eligible Countries: Applications are accepted from around the world.
• Acceptable Course or Subjects: PhD research projects in life sciences cover Institut Curie’s main research domains:
• Biology & Chemistry of Radiations, Cell Signaling & Cancer
• Development, Cancer, Genetics & Epigenetics
• Integrative Tumour Biology, Immunology & Environment
• Multiscale Physics-Biology-Chemistry & Cancer
• Translational Research
• Admissible Criteria: To be eligible, the applicants must meet all the following criteria:
• Early-stage researchers (ESR) shall at the call deadline be in the first four years (full-time equivalent research experience) of their research careers and have not been awarded a doctoral degree.
• Full-time equivalent research experience is measured from the date when a researcher obtained the degree which would formally entitle him or her to embark on a doctorate.
• Applicants may not have resided or carried out their main activity (work, studies, etc.) in
• France for more than 12 months in the three years before January 14 th, 2021.
• Time spent as part of a procedure for obtaining refugee status under the Geneva
• Convention, compulsory national service, and/ or short stays such as holidays are not taken into account.
• Applicants must have a European master degree or equivalent master's degree which would formally entitle them to embark on a doctorate.

Open positions

Project 1

Acentrosomal microtubule organization in neural stem cells
Thesis supervisor(s): Alexandre Baffet
Research group: Cell Biology of Mammalian Neurogenesis

Project 2

Deciphering the role of transcription-replication conflict and R-loop in causing genome instability in breast cancer
Thesis supervisor(s): Chunlong Chen
Research group: Replication Program and Genome Instability

Project 3

Extracellular Vesicles in invasion, metastasis and ferroptosis resistance: a specific role for CD133/Prominin in aggressive gastrointestinal carcinoma

Thesis supervisor(s): Gisela D’Angelo & Sarah Watson
Research group: Structure and Membrane Compartments

Project 4

A multidisciplinary approach to determine the 3-dimensional organization of centromeres in mitosis

Thesis supervisor(s): Ines Drinnenberg
Research group: Evolution of Centromeres and Chromosome Segregation

Project 5

Characterization of the functions of protein arginine methyltransferase 4 (PRMT4/CARM1) in triple-negative breast cancers

Thesis supervisor(s): Thierry Dubois

Research group: Breast Cancer Biology

Project 6

Novel chemical tools to study base-excision DNA repair

Thesis supervisor(s): Anton Granzhan & Sophie Bombard
Research group: Chemistry for Nucleic Acid Recognition

Project 7

Control of gut development and physiology by cytokine signaling
Thesis supervisor(s): Pedro Hernandez
Research group: Development and Homeostasis of Mucosal Tissues

Project 8

Immune and epigenetic biomarkers assessments based on a basket prospective trial with Pembrolizumab and Vorinostat in patients with late-stage squamous cell carcinoma
Thesis supervisor(s): Christophe Le Tourneau & Nicolas Servant
Research group: Bioinformatics and Computational Systems Biology of Cancer

Project 9

Mechanotransduction at the Golgi apparatus
Thesis supervisor(s): Jean-Baptiste Manneville & Stéphanie Miserey-Lenkei
Research group: Molecular Mechanisms of Intracellular Transport

Project 10

Identification and targeting of lncRNA sequence motifs regulating melanoma oncogenesis

Thesis supervisor(s): Alena Shkumatava

Research group: LincRNAs in Vertebrate Development

Project 11

Genetic determinants of tumor microenvironment in high grade serous ovarian carcinomas
Thesis supervisor(s): Marc-Henri Stern & Manuel Rodrigues
Research group: DNA Repair and Uveal Melanoma

Project 12

Comparative mechanisms of spindle assembly dynamics and scaling
Thesis supervisor(s): Phong Tran & François Nedelec
Research group: Cytoskeletal Architecture and Cell Morphogenesis

Application Process

International students willing to apply for the EuReCa PhD Program should inquire about the visa procedure regarding their country. Web site for application & more details: https://training.institut-curie.org/eureca

Benefits: The scholarship winners will receive a salary for the academic year 2021/2022.